49536-6

Influenza virus B RNA [Identifier] in Isolate by Sequencing

Discouraged

Status Information

Status

DISCOURAGED

Comment

Awaiting more information about usage of this term.

Part Descriptions

LP14240-3   Influenza virus B
Influenza virus from the family Orthomyxoviridae are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C viruses are medically relevant to humans. Influenza A and B viruses have a similar structure whereby these viruses each contain eight discrete single-stranded RNA gene segments, each encoding at least one protein. While having a close phylogenetic relationship, influenza virus types A and B manifest very differently. While IAV infects birds, humans and other mammals, influenza B only infects humans and seals. Although both viruses cause human respiratory infection seasonally in temperate climate regions and more continually in the tropics, influenza B is normally less prevalent and causes less severe disease than IAV viruses. Research is ongoing to determine the evolutionary and epidemiological factors that shape the genetic diversity of influenza B virus. PMID: 25812763 [CDC:flu/about/viruses/types] Source: Regenstrief LOINC

LP150045-5   Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

Fully-Specified Name

Component

Influenza virus B RNA

Property

Prid

Time

Pt

System

Isolate

Scale

Nom

Method

Sequencing

Additional Names

Short Name

FLUBV RNA Islt Seq

Display Name

FLUBV RNA Sequencing Nom (Isol)

Consumer Name Alpha Get Info

Influenza B (Flu B)

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.22

Last Updated

Version 2.40

Change Reason

Changed method from Amplification/Sequencing because Amplification always occurs before sequencing

Order vs. Observation

Both

Member of these Groups Get Info

Language Variants Get Info

Related Names

• FLUB
• FLUBV
• FLUV
• high-throughput sequencing
• HTS
• ID
• Identity or presence
• Infectious Disease
• InfectiousDisease
• Influ
• Influenza B
• Influenza B virus
• Islt
• Isol
• Microbiology
• Next generation sequencing
• NGS
• Nominal
• Point in time
• Random
• Ribonucleic acid

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CodeSystem lookup

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.