Version 2.77

Term Description

The prolactin isoforms panel includes individual tests for monomeric, dimeric, and macroprolactin, as well as fraction terms for each isomer and an interpretation based on all of the results. Monomeric prolactin is the most common form of circulating prolactin. The dimeric form ("big-prolactin") has a molecular weight of ~50 kD, and polymeric form ("big-big prolactin") has a molecular weight of ~ 150 kD). Big-big prolactin, known as macroprolactin, and big prolactin are formed in the circulation after secretion of prolactin from the pituitary. They have a longer half-life than monomeric prolactin and are not biologically active. However, typical prolactin assays do not differentiate between the different forms of prolactin, and the presence of big and big-big prolactin can lead to a false diagnosis of hyperprolactinemia. Methods such as PEG precipitation can separate macroprolactin and big prolactin from monomeric prolactin in order to obtain a more accurate measurement of biologically active prolactin, and chromatography can be used to further characterize the isoforms if necessary. PMCID: PMC3719302
Source: Regenstrief LOINC

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
78993-3 Prolactin isoforms panel - Serum or Plasma
Indent15081-3 Prolactin [Units/volume] in Serum or Plasma m[IU]/L
Indent78994-1 Prolactin monomeric [Units/volume] in Serum or Plasma [arb'U]/L
Indent78995-8 Prolactin monomeric/Prolactin in Serum or Plasma %
Indent78985-9 Prolactin.dimeric [Units/volume] in Serum or Plasma [arb'U]/L
Indent78986-7 Prolactin.dimeric/Prolactin in Serum or Plasma %
Indent74953-1 Macroprolactin [Units/volume] in Serum or Plasma [arb'U]/L
Indent78984-2 Macroprolactin/Prolactin in Serum or Plasma %
Indent79398-4 Prolactin isoforms pattern [Interpretation] in Serum or Plasma Narrative

Fully-Specified Name

Component
Prolactin isoforms panel
Property
-
Time
Pt
System
Ser/Plas
Scale
-
Method

Additional Names

Short Name
Prolactin isoforms Pnl SerPl
Display Name
Prolactin isoforms panel
Consumer Name Alpha Get Info
Prolactin isoforms panel, Blood

Basic Attributes

Class
PANEL.CHEM
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.54
Order vs. Observation
Order
Panel Type
Panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Panel isoformas prolactina:Propiedades mixtas (sólo paneles):Punto temporal:Suero o Plasma:-:
es-MX Spanish (Mexico) Panel de isoformas de prolactina:-:Punto temporal:Suero o Plasma:-:
fr-FR French (France) Prolactines isoformes panel:-:Ponctuel:Sérum/Plasma:-:
it-IT Italian (Italy) Isoforme della prolattina, panel:-:Pt:Siero/Plasma:-:
Synonyms: Chimica Panel isoforme della prolattina Plasma Punto nel tempo (episodio) Set di prescrizione chimica Siero Siero o Plasma
nl-NL Dutch (Netherlands) prolactine isovormen panel:-:moment:serum of plasma:-:
zh-CN Chinese (China) 催乳素同工型组套:-:时间点:血清/血浆:-:
Synonyms: PRL;促乳激素;促乳泌素;促乳素;催乳激素;泌乳激素;泌乳素;催乳素（PRL、促乳激素、促乳泌素、促乳素、催乳激素、泌乳激素、泌乳素） 催乳素（PRL、促乳激素、促乳泌素、促乳素、催乳激素、泌乳激素、泌乳素）同工型（同种型、亚型、异构型）组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目） 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.化学试验;化学组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）;化学医嘱组类;医嘱组.化学;医嘱组.化学检验项目;医嘱组类.化学;医嘱组类.化学检验项目;医嘱组类.化学试验;实验室医嘱组类.化学;实验室医嘱组类.化学检验项目;实验室医嘱组类.化学试验 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 多重;多重型;多重标尺类型;多重精度类型 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 时刻;随机;随意;瞬间 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 组 组合 组合医嘱 组合类 组套 血清或血浆

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=78993-3
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/78993-3