Version 2.77

Term Description

Parathyroid hormone is an 84 amino acid peptide designated PTH 1-84. Presence of the first six N-terminal amino acids ("N-terminus") is required for PTH biological activity, so assays that detect biologically active PTH have to, at a minimum, detect the N-terminus. This assay is different from intact parathyroid hormone assays, which are called intact because they detect the PTH molecule before it is degraded into C-terminal and N-terminal fragments by looking for the presence of segments in both the C- and N-terminal sides, but they do not necessarily detect the N-terminus.
Source: Regenstrief LOINC

Part Description

LP268392-0   Parathyrin.1-84
Parathyrin 1-84 (PTH (1-84)) is the biologically active hormone that regulates the calcium and phosphate levels in the circulation. PTH (1-84) is originally produced as a 118-amino acid polypeptide in the parathyroid glands. It is cleaved twice to form a functional 84-amino acid peptide that is stored in the parathyroid cells. The first 34 amino acids bind to the type 1 PTH/PTH-related peptide receptor that is expressed primarily in bone, kidney, cartilage, vessels, and certain developing organs. PMID: 26303600 The half-life of PTH (1-84) is 2-4 minutes, after which it is degraded into a carboxyl (C)- or amino (N)-terminal fragment. The C-fragments have a half-life of 5-10 minutes, are cleared by the kidneys, and can accumulate in the circulation during chronic kidney disease. Some evidence suggests that N-terminally truncated fragment PTH (7-84) may interact with receptors that regulate bone resorption and serum calcium concentrations that could lead to the quantification of other PTH fragments.[https://www.uptodate.com/contents/parathyroid-hormone-assays-and-their-clinical-use] Source: Regenstrief LOINC

Fully-Specified Name

Component
Parathyrin.1-84
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method
IA

Additional Names

Short Name
Parathyrin.1-84 SerPl IA-mCnc
Display Name
Parathyrin.1-84 IA [Mass/Vol]
Consumer Name Alpha Get Info
Parathyrin.1-84, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.65
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG51038-4 Parathyrin.1-84|Pt|Ser/Plas|IA

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Parathormona 1-84:Concentración de masa:Punto temporal:Suero o Plasma:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Paratirina 1-84:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:Inmunoensayo
fr-FR French (France) Parathormone 1-84:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:Immunoanalyse
it-IT Italian (Italy) Paratirina.1-84:MCnc:Pt:Siero/Plasma:Qn:IA
Synonyms: Chimica Concentrazione di Massa Immunoassay Paratormone Plasma Punto nel tempo (episodio) Siero Siero o Plasma
zh-CN Chinese (China) 甲状旁腺素.1-84:质量浓度:时间点:血清/血浆:定量型:免疫测定法
Synonyms: Ⅰ I PTH.1-84 PTH;甲状旁腺激素;甲旁素;甲旁;甲状旁腺激素（Parathyroid hormone，PTH） 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 血清或血浆

Example Units

Unit Source
pg/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=90741-0