LOINC Panel Details 94531-1 SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

94500-6 SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

Term Description

Qualitative detection of SARS coronavirus 2 (SARS-CoV-2) in respiratory specimens by nucleic acid amplification with probe-based detection. Results may be based on multiple assays to determine the presence of the virus in a specimen.
Source: Regenstrief LOINC

Part Descriptions

LP417540-4 SARS coronavirus 2
The 2019 Novel Coronavirus (2019-nCoV) is a coronavirus first identified as the cause of a respiratory illness outbreak in Wuhan, China. Initially, the outbreak was linked to a large seafood and animal market and thought to only be spread by animal to person contact. Within a short time, a growing number of patients who had not been exposed to animal markets were diagnosed with the infection, indicating person-to-person transmission. As of January 2020, infections with 2019-nCoV had been reported internationally due to confirmed cases in travelers from Wuhan. Overall, clinical symptoms appear milder than SARS Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome (MERS) Coronavirus (MERS-CoV) infections as do the fatality rate and transmissibility. PMID: 31953166 Reported illnesses range from minor or no respiratory symptoms to severe acute respiratory illness and death.

The full genome of the 2019-nCoV was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Source: LOINC

Reference Information

Type	Source	Reference
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing

Fully-Specified Name

Component: SARS coronavirus 2 RNA
Property: PrThr
Time: Pt
System: Respiratory System Specimen
Scale: Ord
Method: Probe.amp.tar

Additional Names

Short Name: SARS-CoV-2 RNA Resp Ql NAA+probe
Display Name: SARS-CoV-2 (COVID-19) RNA NAA+probe Ql (Respiratory system specimen)
Consumer Name Alpha Get Info: SARS-CoV-2 (COVID-19), Respiratory system specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.75
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Both
Common Test Rank Get Info: 65

Example Answer List LL2021-5

Answer	Code	Score	Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6
Invalid Copyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value)			LA15841-2

Member of these Panels

LOINC	Long Common Name
101721-9	Deprecated SARS-CoV-2 (COVID-19) in Respiratory specimen by NAA with probe detection
103202-8	Deprecated SARS-CoV-2 (COVID-19) RNA in Respiratory specimen by NAA with probe detection
95941-1	Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
95380-2	Influenza virus A and B and SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
95422-2	Influenza virus A and B and SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection
92143-7	Respiratory pathogens DNA and RNA panel - Respiratory system specimen by NAA with probe detection
94499-1	Respiratory viral pathogens DNA and RNA panel - Respiratory system specimen Qualitative by NAA with probe detection
96094-8	SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG50983-2	SARS coronavirus 2 RNA\|PrThr\|Sys:ANYResp
LG51017-8	SARSCoV2 detection
LG51019-4	SARSCoV2 molecular detection

Language Variants Get Info

Tag	Language	Translation
de-AT	German (Austria)	Synonyms: SCV2-RNA ql. /RT P
de-DE	German (Germany)	SARS-Coronavirus 2 RNA:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES	Spanish (Spain)	Panel del SARS-CoV-2 (COVID-19) RNA:PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Sonda con amplificación dirigida Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	ARN del coronavirus 2 del SARS:Presencia o umbral:Punto temporal:Espécimen respiratorio:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Coronavirus SARS-CoV-2 ARN:Présence/Seuil:Ponctuel:Respiratoire:Qualitatif:PCR amplification de cible
fr-CA	French (Canada)	coronavirus 2 du SRAS , ARN:Présence-Seuil:Temps ponctuel:Échantillon du système respiratoire:Ordinal:Sonde avec amplification de la cible
it-IT	Italian (Italy)	SARS coronavirus 2 RNA:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar Synonyms: Campione da Apparato Respiratorio Coronavirus della SARS Microbiologia Presenza o Soglia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-CoV-2 RNA:aanwezigheid:moment:respiratoir monster:ordinaal:probe-detectie Synonyms: probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
uk-UA	Ukrainian (Ukraine)	SARS коронавірус 2 РНК:Наявність або Поріг:МоментЧасу:Респіраторний зразок:Порядково:Зонд-детекція. цільова аміпліфікація НК Synonyms: 2019 Novel Coronavirus; 2019-nCoV; 3 Self-Sustaining Sequence Replication; 3SR SR; Amplif; Amplification; Amplified; Corona virus; COVID19; COVID-19; DNA NUCLEIC ACID PROBE; DNA probe; ID; II; Infectious Disease; InfectiousDisease; LAT; LCR; Ligase chain reaction; Ligation-activated transcription; Microbiology; NAA+probe; NAAT; NASBA; Nucleic acid sequence based analysis; Ordinal; PCR; Point in time; Polymerase chain reaction; PR; Probe amp; Probe with ampification; Probe with target amplification; QBR; QL; Qual; Qualitative; Random; Ribonucleic acid; SARS Coronavirus 1; SARS-CoV; SARS-CoV-1; SARS-CoV-2; Screen; SDA; Severe Acute Respiratory Syndrome; Strand Displacement Amplification; TMA; Transcription mediated amplification; Viral Pneumonias; Wuhan coronavirus
zh-CN	Chinese (China)	SARS 冠状病毒 2 RNA:存在情况或阈值:时间点:呼吸系统标本:序数型:探针法.基因扩增.靶向 Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ II SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向受检物呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间样品样本核糖核酸;Ribonucleic acid 经过扩增的脱氧核糖核酸探针试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

94745-7 SARS-CoV-2 (COVID-19) RNA [Cycle Threshold #] in Respiratory system specimen by NAA with probe detection

Part Descriptions

LP417540-4 SARS coronavirus 2
The 2019 Novel Coronavirus (2019-nCoV) is a coronavirus first identified as the cause of a respiratory illness outbreak in Wuhan, China. Initially, the outbreak was linked to a large seafood and animal market and thought to only be spread by animal to person contact. Within a short time, a growing number of patients who had not been exposed to animal markets were diagnosed with the infection, indicating person-to-person transmission. As of January 2020, infections with 2019-nCoV had been reported internationally due to confirmed cases in travelers from Wuhan. Overall, clinical symptoms appear milder than SARS Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome (MERS) Coronavirus (MERS-CoV) infections as do the fatality rate and transmissibility. PMID: 31953166 Reported illnesses range from minor or no respiratory symptoms to severe acute respiratory illness and death.

The full genome of the 2019-nCoV was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Source: LOINC

Reference Information

Type	Source	Reference
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing

Fully-Specified Name

Component: SARS coronavirus 2 RNA
Property: ThreshNum
Time: Pt
System: Respiratory System Specimen
Scale: Qn
Method: Probe.amp.tar

Additional Names

Short Name: SARS-CoV-2 RNA Ct Resp Qn NAA+probe
Display Name: SARS-CoV-2 (COVID-19) RNA NAA+probe (Respiratory system specimen) [ThreshNum]
Consumer Name Alpha Get Info: SARS-CoV-2 (COVID-19), Respiratory system specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.75
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
96094-8	SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG51017-8	SARSCoV2 detection
LG51019-4	SARSCoV2 molecular detection

Language Variants Get Info

Tag	Language	Translation
de-AT	German (Austria)	Synonyms: SARS-CoV-2-RNA /RT PCR
de-DE	German (Germany)	SARS-Coronavirus 2 RNA:Ct-Wert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Quantitativ:Zielfragmentamplifikation mit Sondendetektion
es-ES	Spanish (Spain)	Panel del SARS-CoV-2 (COVID-19) RNA:ThreshNnum:Punto temporal:Muestra del sistema respiratorio:Qn:Sonda con amplificación dirigida Synonyms: Cuantitativo Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	ARN del coronavirus 2 del SARS:ThreshNum:Punto temporal:Espécimen respiratorio:Cuantitativo:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Coronavirus SARS-CoV-2 ARN:Cycle seuil:Ponctuel:Respiratoire:Numérique:PCR amplification de cible
it-IT	Italian (Italy)	SARS coronavirus 2 RNA:Thresnum:Pt:Campione da Sistema Respiratorio:Qn:Sonda.amp.tar Synonyms: Campione da Apparato Respiratorio Coronavirus della SARS Limite di soglia Microbiologia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-CoV-2 RNA:drempelwaarde nummer:moment:respiratoir monster:kwantitatief:probe-detectie Synonyms: probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
zh-CN	Chinese (China)	SARS 冠状病毒 2 RNA:阈值循环圈数:时间点:呼吸系统标本:定量型:探针法.基因扩增.靶向 Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ II SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒供检查用的材料;待检物;待试验物;样品;样本;试料;试样借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间样品样本核糖核酸;Ribonucleic acid 界值数;界限数;阀值数;临界值数;阈值循环数;阈值数;达到阈值时的循环圈数;荧光信号到达设定阈值时所经历的循环数;Ct 值;Cycle threshold;循环阈值经过扩增的脱氧核糖核酸探针试样

Example Units

Unit	Source
{Ct_value}	Example UCUM Units

96763-8 SARS-CoV-2 (COVID-19) E gene [Presence] in Respiratory system specimen by NAA with probe detection

Term Description

Qualitative detection of nucleic acids within the envelope (E) gene specific for SARS coronavirus 2 (SARS-CoV-2) in respiratory specimens by nucleic acid amplification with probe-based detection.
Source: Regenstrief LOINC

Reference Information

Type	Source	Reference
Mapping Guidance	LOINC	Take caution when mapping LOINC codes to molecular tests for SARS coronaviruses that target nucleic acids within the E gene. Such assays detect either SARS-related coronavirus or SARS-CoV-2, depending on the targeted region within the E gene. Assays that are non-specific to only SARS-CoV-2 may say they are "positive" for SARS-CoV-2, but only because it is the primary circulating virus during the pandemic. These assays actually detect any SARS-related coronaviruses since they target a region in the E gene that contains sequence homology to other known coronaviruses. Other assays target a region in the E gene that is specific for SARS-CoV-2. The LIVD file contains current LOINC code mappings to many IVD tests [https://www.cdc.gov/csels/dls/sars-cov-2-livd-codes.html]. You may also contact the manufacturer directly to verify LOINC code mappings.
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing

Fully-Specified Name

Component: SARS coronavirus 2 E gene
Property: PrThr
Time: Pt
System: Respiratory System Specimen
Scale: Ord
Method: Probe.amp.tar

Additional Names

Short Name: SARS-CoV-2 E gene Resp Ql NAA+probe
Display Name: SARS-CoV-2 (COVID-19) E gene NAA+probe Ql (Respiratory system specimen)
Consumer Name Alpha Get Info: SARS-CoV-2 (COVID-19) E gene, Respiratory system specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.70
Last Updated: Version 2.75
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Both

Example Answer List LL360-9

Answer	Code	Score	Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Member of these Panels

LOINC	Long Common Name
95941-1	Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
96094-8	SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG51017-8	SARSCoV2 detection
LG51019-4	SARSCoV2 molecular detection

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-Coronavirus 2 E-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES	Spanish (Spain)	Gen E del SARS-CoV-2 (COVID-19):PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Sonda con amplificación dirigida Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	Gen del coronavirus 2 E del SARS:PrThr:Punto temporal:Respiratorio:Ordinal:Probe.amp.tar
fr-FR	French (France)	Coronavirus SARS-CoV-2 gène E:Présence/Seuil:Ponctuel:Respiratoire:Qualitatif:PCR amplification de cible
it-IT	Italian (Italy)	SARS coronavirus 2, gene E:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar Synonyms: Campione da Apparato Respiratorio Coronavirus della SARS Gene E di SARS coronavirus 2;gene E di SARS-CoV-2 (COVID-19) Microbiologia Presenza o Soglia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-CoV-2 E-gen:aanwezigheid:moment:respiratoir monster:ordinaal:probe-detectie Synonyms: probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
zh-CN	Chinese (China)	SARS 冠状病毒 2 E 基因:存在情况或阈值:时间点:呼吸系统标本:序数型:探针法.基因扩增.靶向 Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ E 型 II SARS 冠状病毒 2 E 基因;2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向受检物呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间样品样本经过扩增的脱氧核糖核酸探针试样遗传基因;遗传因子;吉恩;生物基因

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

96764-6 SARS-CoV-2 (COVID-19) E gene [Cycle Threshold #] in Respiratory system specimen by NAA with probe detection

Term Description

Quantitative detection (Cq value) of nucleic acids within the envelope (E) gene specific for SARS coronavirus 2 (SARS-CoV-2) in respiratory specimens by nucleic acid amplification with probe-based detection.
Source: Regenstrief LOINC

Reference Information

Type	Source	Reference
Mapping Guidance	LOINC	Take caution when mapping LOINC codes to molecular tests for SARS coronaviruses that target nucleic acids within the E gene. Such assays detect either SARS-related coronavirus or SARS-CoV-2, depending on the targeted region within the E gene. Assays that are non-specific to only SARS-CoV-2 may say they are "positive" for SARS-CoV-2, but only because it is the primary circulating virus during the pandemic. These assays actually detect any SARS-related coronaviruses since they target a region in the E gene that contains sequence homology to other known coronaviruses. Other assays target a region in the E gene that is specific for SARS-CoV-2. The LIVD file contains current LOINC code mappings to many IVD tests [https://www.cdc.gov/csels/dls/sars-cov-2-livd-codes.html]. You may also contact the manufacturer directly to verify LOINC code mappings.
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing

Fully-Specified Name

Component: SARS coronavirus 2 E gene
Property: ThreshNum
Time: Pt
System: Respiratory System Specimen
Scale: Qn
Method: Probe.amp.tar

Additional Names

Short Name: SARS-CoV-2 E gene Ct Resp Qn NAA+probe
Display Name: SARS-CoV-2 (COVID-19) E gene NAA+probe (Respiratory system specimen) [ThreshNum]
Consumer Name Alpha Get Info: SARS-CoV-2 (COVID-19) E gene, Respiratory system specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.70
Last Updated: Version 2.75
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
96094-8	SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG51017-8	SARSCoV2 detection
LG51019-4	SARSCoV2 molecular detection

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-Coronavirus 2 E-Gen:Ct-Wert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Quantitativ:Zielfragmentamplifikation mit Sondendetektion
es-ES	Spanish (Spain)	Gen E del SARS-CoV-2 (COVID-19):ThreshNnum:Punto temporal:Muestra del sistema respiratorio:Qn:Sonda con amplificación dirigida Synonyms: Cuantitativo Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	Gen del coronavirus 2 E del SARS:ThreshNum:Punto temporal:Respiratorio:Cuantitativo:Probe.amp.tar
fr-FR	French (France)	Coronavirus SARS-CoV-2 gène E:Cycle seuil:Ponctuel:Respiratoire:Numérique:PCR amplification de cible
it-IT	Italian (Italy)	SARS coronavirus 2, gene E:Thresnum:Pt:Campione da Sistema Respiratorio:Qn:Sonda.amp.tar Synonyms: Campione da Apparato Respiratorio Coronavirus della SARS Gene E di SARS coronavirus 2;gene E di SARS-CoV-2 (COVID-19) Limite di soglia Microbiologia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-CoV-2 E-gen:drempelwaarde nummer:moment:respiratoir monster:kwantitatief:probe-detectie Synonyms: probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
zh-CN	Chinese (China)	SARS 冠状病毒 2 E 基因:阈值循环圈数:时间点:呼吸系统标本:定量型:探针法.基因扩增.靶向 Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ E 型 II SARS 冠状病毒 2 E 基因;2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒供检查用的材料;待检物;待试验物;样品;样本;试料;试样借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间样品样本界值数;界限数;阀值数;临界值数;阈值循环数;阈值数;达到阈值时的循环圈数;荧光信号到达设定阈值时所经历的循环数;Ct 值;Cycle threshold;循环阈值经过扩增的脱氧核糖核酸探针试样遗传基因;遗传因子;吉恩;生物基因

Example Units

Unit	Source
{Ct_value}	Example UCUM Units

94533-7 SARS-CoV-2 (COVID-19) N gene [Presence] in Respiratory system specimen by NAA with probe detection

Term Description

Qualitative detection of nucleic acids within the nucleoprotein (N) gene of SARS coronavirus 2 (SARS-CoV-2) in respiratory specimens by nucleic acid amplification with probe-based detection. Various assays have been developed that contain primer-probe sets targeting N gene. [https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance]
Source: Regenstrief LOINC

Part Descriptions

LP417599-0 SARS coronavirus 2 N gene
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC: coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] Source: Regenstrief LOINC

Reference Information

Type	Source	Reference
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing

Fully-Specified Name

Component: SARS coronavirus 2 N gene
Property: PrThr
Time: Pt
System: Respiratory System Specimen
Scale: Ord
Method: Probe.amp.tar

Additional Names

Short Name: SARS-CoV-2 N gene Resp Ql NAA+probe
Display Name: SARS-CoV-2 (COVID-19) N gene NAA+probe Ql (Respiratory system specimen)
Consumer Name Alpha Get Info: SARS-CoV-2 (COVID-19) N gene, Respiratory system specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.75
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Both

Example Answer List LL2009-0

Answer	Code	Score	Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6
Equivocal Copyright http://snomed.info/sct ID:42425007 Equivocal (qualifier value)			LA11885-3

Member of these Panels

LOINC	Long Common Name
95941-1	Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
95422-2	Influenza virus A and B and SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection
92143-7	Respiratory pathogens DNA and RNA panel - Respiratory system specimen by NAA with probe detection
94499-1	Respiratory viral pathogens DNA and RNA panel - Respiratory system specimen Qualitative by NAA with probe detection
96094-8	SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG51004-6	SARS coronavirus 2 N gene\|PrThr\|Sys:ANYResp
LG51017-8	SARSCoV2 detection
LG51019-4	SARSCoV2 molecular detection

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-Coronavirus 2 N-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES	Spanish (Spain)	Gen N de SARS-CoV-2 (COVID-19):PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Sonda con amplificación dirigida Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	Gen del coronavirus 2 N del SARS:Presencia o umbral:Punto temporal:Espécimen respiratorio:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Coronavirus SARS-CoV-2 gène N:Présence/Seuil:Ponctuel:Respiratoire:Qualitatif:PCR amplification de cible
fr-CA	French (Canada)	gène N du coronavirus 2 du SRAS:Présence-Seuil:Temps ponctuel:Échantillon du système respiratoire:Ordinal:Sonde avec amplification de la cible
it-IT	Italian (Italy)	SARS coronavirus 2, gene N:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar Synonyms: Campione da Apparato Respiratorio Coronavirus della SARS Gene N di SARS-CoV-2 (COVID-19) Microbiologia Presenza o Soglia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-CoV-2 N-gen:aanwezigheid:moment:respiratoir monster:ordinaal:probe-detectie Synonyms: evere acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
zh-CN	Chinese (China)	SARS 冠状病毒 2 N 基因:存在情况或阈值:时间点:呼吸系统标本:序数型:探针法.基因扩增.靶向 Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ II N 型 SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向受检物呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间样品样本经过扩增的脱氧核糖核酸探针试样遗传基因;遗传因子;吉恩;生物基因

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

94757-2 SARS-CoV-2 (COVID-19) N gene [Presence] in Respiratory system specimen by Nucleic acid amplification using CDC primer-probe set N2

Term Description

Qualitative detection of nucleic acids within the N gene of SARS coronavirus 2 (SARS-CoV-2) in respiratory specimens by nucleic acid amplification with probe-based detection using the N2 primer-probe set developed by the Centers for Disease Control and Prevention (CDC). [CDC: coronavirus/COVID-19/lab/]
Source: Regenstrief LOINC

Part Descriptions

LP417599-0 SARS coronavirus 2 N gene
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC: coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] Source: Regenstrief LOINC

Reference Information

Type	Source	Reference
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing

Fully-Specified Name

Component: SARS coronavirus 2 N gene
Property: PrThr
Time: Pt
System: Respiratory System Specimen
Scale: Ord
Method: Probe.amp.tar.CDC primer-probe set N2

Additional Names

Short Name: SARS-CoV-2 N gene Resp Ql NAA N2
Display Name: SARS-CoV-2 (COVID-19) N gene NAA+probe CDC primer-probe set N2 Ql (Respiratory system specimen)
Consumer Name Alpha Get Info: SARS-CoV-2 (COVID-19) N gene, Respiratory system specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.75
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Observation

Example Answer List LL744-4

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Member of these Panels

LOINC	Long Common Name
96094-8	SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG51004-6	SARS coronavirus 2 N gene\|PrThr\|Sys:ANYResp
LG51017-8	SARSCoV2 detection
LG51019-4	SARSCoV2 molecular detection

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-Coronavirus 2 N-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion mit Primer-Sondenset N2 des Center for Disease Control and Prevention
es-ES	Spanish (Spain)	Gen N de SARS-CoV-2 (COVID-19):PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Amplificación de ácido nucleico utilizando el conjunto de cebadores y sondas N2 de los Centros para el Control y la Prevención de Enfermedades Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	Gen del coronavirus 2 N del SARS:Presencia o umbral:Punto temporal:Espécimen respiratorio:Ordinal:Amplificación de ácidos nucleicos utilizando el conjunto de cebadores y sondas de los Centros para el Control y la Prevención de Enfermedades N2
fr-FR	French (France)	Coronavirus SARS-CoV-2 gène N:Présence/Seuil:Ponctuel:Respiratoire:Qualitatif:PCR amplification de cible N2
it-IT	Italian (Italy)	SARS coronavirus 2, gene N:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar.CDC set primer-sonda N2 Synonyms: Amplificazione degli acidi nucleici utilizzando il set primer-sonda N2 dei Centri per il controllo e la prevenzione della malattia Campione da Apparato Respiratorio Coronavirus della SARS Gene N di SARS-CoV-2 (COVID-19) Microbiologia Presenza o Soglia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-CoV-2 N-gen:aanwezigheid:moment:respiratoir monster:ordinaal:probe-detectie met CDC primer-probe set N2 Synonyms: evere acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 moleculaire techniek (PCR) met CDC-primer-probe set N2 probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
zh-CN	Chinese (China)	SARS 冠状病毒 2 N 基因:存在情况或阈值:时间点:呼吸系统标本:序数型:探针法.基因扩增.靶向.CDC 引物-探针组 N2 Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ II N 型 SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向受检物呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性探针法.扩增.靶向.CDC（美国疾病控制与预防中心）引物-探针组（探针集合、探针集、探针组合） N2 时刻;随机;随意;瞬间样品样本疾病预防控制中心;疾控中心;Centers for Disease Control and Prevention;美国疾病控制与预防中心;美国疾病控制和预防中心;美国疾病预防控制中心经过扩增的脱氧核糖核酸探针试样遗传基因;遗传因子;吉恩;生物基因

94756-4 SARS-CoV-2 (COVID-19) N gene [Presence] in Respiratory system specimen by Nucleic acid amplification using CDC primer-probe set N1

Term Description

Qualitative detection of nucleic acids within the N gene of SARS coronavirus 2 (SARS-CoV-2) in respiratory specimens by nucleic acid amplification with probe-based detection using the N1 primer-probe set developed by the Centers for Disease Control and Prevention (CDC). [CDC: coronavirus/COVID-19/lab/]
Source: Regenstrief LOINC

Part Descriptions

LP417599-0 SARS coronavirus 2 N gene
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC: coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] Source: Regenstrief LOINC

Reference Information

Type	Source	Reference
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing

Fully-Specified Name

Component: SARS coronavirus 2 N gene
Property: PrThr
Time: Pt
System: Respiratory System Specimen
Scale: Ord
Method: Probe.amp.tar.CDC primer-probe set N1

Additional Names

Short Name: SARS-CoV-2 N gene Resp Ql NAA N1
Display Name: SARS-CoV-2 (COVID-19) N gene NAA+probe CDC primer-probe set N1 Ql (Respiratory system specimen)
Consumer Name Alpha Get Info: SARS-CoV-2 (COVID-19) N gene, Respiratory system specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.75
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Observation

Example Answer List LL744-4

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Member of these Panels

LOINC	Long Common Name
96094-8	SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG51004-6	SARS coronavirus 2 N gene\|PrThr\|Sys:ANYResp
LG51017-8	SARSCoV2 detection
LG51019-4	SARSCoV2 molecular detection

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-Coronavirus 2 N-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion mit Primer-Sondenset N1 des Center for Disease Control and Prevention
es-ES	Spanish (Spain)	Gen N de SARS-CoV-2 (COVID-19):PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Amplificación de ácido nucleico utilizando el conjunto de cebadores y sondas N1 de los Centros para el Control y la Prevención de Enfermedades Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	Gen del coronavirus 2 N del SARS:Presencia o umbral:Punto temporal:Espécimen respiratorio:Ordinal:Amplificación de ácido nucleico utilizando el conjunto de cebadores y sondas de los Centros para el Control y la Prevención de Enfermedades N1
fr-FR	French (France)	Coronavirus SARS-CoV-2 gène N:Présence/Seuil:Ponctuel:Respiratoire:Qualitatif:PCR amplification de cible N1
it-IT	Italian (Italy)	SARS coronavirus 2, gene N:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar.CDC set primer-sonda N1 Synonyms: Amplificazione degli acidi nucleici utilizzando il set primer-sonda N1 dei Centri per il controllo e la prevenzione della malattia Campione da Apparato Respiratorio Coronavirus della SARS Gene N di SARS-CoV-2 (COVID-19) Microbiologia Presenza o Soglia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-CoV-2 N-gen:aanwezigheid:moment:respiratoir monster:ordinaal:probe-detectie met CDC primer-probe set N1 Synonyms: evere acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 moleculaire techniek (PCR) met CDC-primer-probe set N1 probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
zh-CN	Chinese (China)	SARS 冠状病毒 2 N 基因:存在情况或阈值:时间点:呼吸系统标本:序数型:探针法.基因扩增.靶向.CDC 引物-探针组 N1 Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ II N 型 SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向受检物呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性探针法.扩增.靶向.CDC（美国疾病控制与预防中心）引物-探针组（探针集合、探针集、探针组合） N1 时刻;随机;随意;瞬间样品样本疾病预防控制中心;疾控中心;Centers for Disease Control and Prevention;美国疾病控制与预防中心;美国疾病控制和预防中心;美国疾病预防控制中心经过扩增的脱氧核糖核酸探针试样遗传基因;遗传因子;吉恩;生物基因

95522-9 SARS-CoV-2 (COVID-19) N gene [Log #/volume] (viral load) in Respiratory system specimen by NAA with probe detection

Part Descriptions

LP417599-0 SARS coronavirus 2 N gene
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC: coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] Source: Regenstrief LOINC

Reference Information

Type	Source	Reference
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing

Fully-Specified Name

Component: SARS coronavirus 2 N gene
Property: LnCnc
Time: Pt
System: Respiratory System Specimen
Scale: Qn
Method: Probe.amp.tar

Additional Names

Short Name: SARS-CoV-2 N gene Resp NAA+probe-Log#
Display Name: SARS-CoV-2 (COVID-19) N gene NAA+probe (Respiratory system specimen) [Log #/Vol]
Consumer Name Alpha Get Info: SARS-CoV-2 (COVID-19) N gene, Respiratory system specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.69
Last Updated: Version 2.75
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
96094-8	SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG51017-8	SARSCoV2 detection
LG51019-4	SARSCoV2 molecular detection

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-Coronavirus 2 N-Gen:Logarithmische Anzahl pro Volumen:Zeitpunkt:Probenmaterial vom Respirationstrakt:Quantitativ:Zielfragmentamplifikation mit Sondendetektion
es-ES	Spanish (Spain)	Gen N de SARS-CoV-2 (COVID-19):Logaritmo de concentración:Punto temporal:Muestra del sistema respiratorio:Qn:Sonda con amplificación dirigida Synonyms: Cuantitativo Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	Gen del coronavirus 2 N del SARS:Concentración del número de registro:Punto temporal:Espécimen respiratorio:Cuantitativo:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Coronavirus SARS-CoV-2 gène N:Log Nombre/Volume:Ponctuel:Respiratoire:Numérique:PCR amplification de cible
fr-CA	French (Canada)	gène N du coronavirus 2 du SRAS:Concentration logarithmique:Temps ponctuel:Échantillon du système respiratoire:Quantitatif:Sonde avec amplification de la cible
it-IT	Italian (Italy)	SARS coronavirus 2, gene N:LnCnc:Pt:Campione da Sistema Respiratorio:Qn:Sonda.amp.tar Synonyms: Campione da Apparato Respiratorio Concentrazione logaritmica Coronavirus della SARS Gene N di SARS-CoV-2 (COVID-19) Microbiologia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-CoV-2 N-gen:logaritmisch aantal/volume:moment:respiratoir monster:kwantitatief:probe-detectie Synonyms: evere acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
zh-CN	Chinese (China)	SARS 冠状病毒 2 N 基因:对数型数量或计数浓度:时间点:呼吸系统标本:定量型:探针法.基因扩增.靶向 Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ II N 型 SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒供检查用的材料;待检物;待试验物;样品;样本;试料;试样借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）对数型数量或计数浓度探针法.扩增.靶向对数型数量浓度探针法.基因扩增.靶向对数型数量浓度探针法.扩增.靶向对数型数量浓度;对数型计数浓度;数量或计数型浓度之对数对数型计数浓度探针法.基因扩增.靶向对数型计数浓度探针法.扩增.靶向微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间样品样本病毒负荷病毒负荷量病毒负载病毒载量病毒载量（Viral load）经过扩增的脱氧核糖核酸探针试样遗传基因;遗传因子;吉恩;生物基因

Example Units

Unit	Source
{Log_copies}/mL	Example UCUM Units

95521-1 SARS-CoV-2 (COVID-19) N gene [#/volume] (viral load) in Respiratory system specimen by NAA with probe detection

Part Descriptions

LP417599-0 SARS coronavirus 2 N gene
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC: coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] Source: Regenstrief LOINC

Reference Information

Type	Source	Reference
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing

Fully-Specified Name

Component: SARS coronavirus 2 N gene
Property: NCnc
Time: Pt
System: Respiratory System Specimen
Scale: Qn
Method: Probe.amp.tar

Additional Names

Short Name: SARS-CoV-2 N gene # Resp NAA+probe
Display Name: SARS-CoV-2 (COVID-19) N gene NAA+probe (Respiratory system specimen) [#/Vol]
Consumer Name Alpha Get Info: SARS-CoV-2 (COVID-19) N gene, Respiratory system specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.69
Last Updated: Version 2.75
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
96094-8	SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG51017-8	SARSCoV2 detection
LG51019-4	SARSCoV2 molecular detection

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-Coronavirus 2 N-Gen:Anzahl pro Volumen:Zeitpunkt:Probenmaterial vom Respirationstrakt:Quantitativ:Zielfragmentamplifikation mit Sondendetektion
es-ES	Spanish (Spain)	Gen N de SARS-CoV-2 (COVID-19):Concentración de número:Punto temporal:Muestra del sistema respiratorio:Qn:Sonda con amplificación dirigida Synonyms: Cuantitativo Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	Gen del coronavirus 2 N del SARS:Concentración numérica:Punto temporal:Espécimen respiratorio:Cuantitativo:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Coronavirus SARS-CoV-2 gène N:Nombre/Volume:Ponctuel:Respiratoire:Numérique:PCR amplification de cible
fr-CA	French (Canada)	gène N du coronavirus 2 du SRAS:Concentration numérique:Temps ponctuel:Échantillon du système respiratoire:Quantitatif:Sonde avec amplification de la cible
it-IT	Italian (Italy)	SARS coronavirus 2, gene N:NCnc:Pt:Campione da Sistema Respiratorio:Qn:Sonda.amp.tar Synonyms: Campione da Apparato Respiratorio Concentrazione Numerica Coronavirus della SARS Gene N di SARS-CoV-2 (COVID-19) Microbiologia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-CoV-2 N-gen:aantal/volume:moment:respiratoir monster:kwantitatief:probe-detectie Synonyms: evere acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
zh-CN	Chinese (China)	SARS 冠状病毒 2 N 基因:计数型浓度:时间点:呼吸系统标本:定量型:探针法.基因扩增.靶向 Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ II N 型 SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒供检查用的材料;待检物;待试验物;样品;样本;试料;试样借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向单位体积内的数量或计数;数量型浓度(单位体积);数量或计数型浓度(计数/体积);数量或计数型浓度(单位体积);计数型浓度(单位体积) 受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性数量型浓度探针法.基因扩增.靶向数量型浓度探针法.扩增.靶向数量或计数型浓度探针法.扩增.靶向时刻;随机;随意;瞬间样品样本病毒负荷病毒负荷量病毒负载病毒载量病毒载量（Viral load）经过扩增的脱氧核糖核酸探针计数型浓度探针法.基因扩增.靶向计数型浓度探针法.扩增.靶向试样遗传基因;遗传因子;吉恩;生物基因

Example Units

Unit	Source
{copies}/mL	Example UCUM Units

94534-5 SARS-CoV-2 (COVID-19) RdRp gene [Presence] in Respiratory system specimen by NAA with probe detection

Term Description

Qualitative detection of nucleic acids within the RdRp gene of SARS coronavirus 2 (SARS-CoV-2) in respiratory specimens by nucleic acid amplification with probe-based detection. Various assays have been developed that contain primer-probe sets targeting RdRp gene. [https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance]
Source: Regenstrief LOINC

Part Descriptions

LP417598-2 SARS coronavirus 2 RdRp gene
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC: coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] Source: Regenstrief LOINC

Reference Information

Type	Source	Reference
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing

Fully-Specified Name

Component: SARS coronavirus 2 RdRp gene
Property: PrThr
Time: Pt
System: Respiratory System Specimen
Scale: Ord
Method: Probe.amp.tar

Additional Names

Short Name: SARS-CoV-2 RdRp Resp Ql NAA+probe
Display Name: SARS-CoV-2 (COVID-19) RdRp gene NAA+probe Ql (Respiratory system specimen)
Consumer Name Alpha Get Info: SARS-CoV-2 (COVID-19) RdRp gene, Respiratory system specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.75
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Both

Example Answer List LL2009-0

Answer	Code	Score	Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6
Equivocal Copyright http://snomed.info/sct ID:42425007 Equivocal (qualifier value)			LA11885-3

Member of these Panels

LOINC	Long Common Name
92143-7	Respiratory pathogens DNA and RNA panel - Respiratory system specimen by NAA with probe detection
94499-1	Respiratory viral pathogens DNA and RNA panel - Respiratory system specimen Qualitative by NAA with probe detection
96094-8	SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG51047-5	SARS coronavirus 2 RdRp gene\|PrThr\|Sys:ANYResp
LG51017-8	SARSCoV2 detection
LG51019-4	SARSCoV2 molecular detection

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-Coronavirus 2 RdRp-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES	Spanish (Spain)	Gen RdRp de SARS-CoV-2 (COVID-19):PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Sonda con amplificación dirigida Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	Gen RdRp del coronavirus 2 del SARS:Presencia o umbral:Punto temporal:Espécimen respiratorio:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Coronavirus SARS-CoV-2 gène RdRp:Présence/Seuil:Ponctuel:Respiratoire:Qualitatif:PCR amplification de cible
fr-CA	French (Canada)	gène RdRp du coronavirus 2 du SRAS:Présence-Seuil:Temps ponctuel:Échantillon du système respiratoire:Ordinal:Sonde avec amplification de la cible
it-IT	Italian (Italy)	SARS coronavirus 2, gene RdRp:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar Synonyms: Campione da Apparato Respiratorio Coronavirus della SARS Gene RdRp di SARS-CoV-2 (COVID-19) Microbiologia Presenza o Soglia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-CoV-2 RdRp-gen:aanwezigheid:moment:respiratoir monster:ordinaal:probe-detectie Synonyms: probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
zh-CN	Chinese (China)	SARS 冠状病毒 2 RdRp 基因:存在情况或阈值:时间点:呼吸系统标本:序数型:探针法.基因扩增.靶向 Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ II SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向受检物呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间样品样本经过扩增的脱氧核糖核酸探针试样遗传基因;遗传因子;吉恩;生物基因

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

94646-7 SARS-CoV-2 (COVID-19) RdRp gene [Cycle Threshold #] in Respiratory system specimen by NAA with probe detection

Part Descriptions

LP417598-2 SARS coronavirus 2 RdRp gene
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC: coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] Source: Regenstrief LOINC

Reference Information

Type	Source	Reference
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing

Fully-Specified Name

Component: SARS coronavirus 2 RdRp gene
Property: ThreshNum
Time: Pt
System: Respiratory System Specimen
Scale: Qn
Method: Probe.amp.tar

Additional Names

Short Name: SARS-CoV-2 RdRp Ct Resp Qn NAA+probe
Display Name: SARS-CoV-2 (COVID-19) RdRp gene NAA+probe (Respiratory system specimen) [ThreshNum]
Consumer Name Alpha Get Info: SARS-CoV-2 (COVID-19) RdRp gene, Respiratory system specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.75
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
96094-8	SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG51017-8	SARSCoV2 detection
LG51019-4	SARSCoV2 molecular detection

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-Coronavirus 2 RdRp-Gen:Ct-Wert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Quantitativ:Zielfragmentamplifikation mit Sondendetektion
es-ES	Spanish (Spain)	Gen RdRp de SARS-CoV-2 (COVID-19):ThreshNnum:Punto temporal:Muestra del sistema respiratorio:Qn:Sonda con amplificación dirigida Synonyms: Cuantitativo Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	Gen RdRp del coronavirus 2 del SARS:ThreshNum:Punto temporal:Espécimen respiratorio:Cuantitativo:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Coronavirus SARS-CoV-2 gène RdRp:Cycle seuil:Ponctuel:Respiratoire:Numérique:PCR amplification de cible
it-IT	Italian (Italy)	SARS coronavirus 2, gene RdRp:Thresnum:Pt:Campione da Sistema Respiratorio:Qn:Sonda.amp.tar Synonyms: Campione da Apparato Respiratorio Coronavirus della SARS Gene RdRp di SARS-CoV-2 (COVID-19) Limite di soglia Microbiologia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-CoV-2 RdRp-gen:drempelwaarde nummer:moment:respiratoir monster:kwantitatief:probe-detectie Synonyms: probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
zh-CN	Chinese (China)	SARS 冠状病毒 2 RdRp 基因:阈值循环圈数:时间点:呼吸系统标本:定量型:探针法.基因扩增.靶向 Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ II SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒供检查用的材料;待检物;待试验物;样品;样本;试料;试样借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间样品样本界值数;界限数;阀值数;临界值数;阈值循环数;阈值数;达到阈值时的循环圈数;荧光信号到达设定阈值时所经历的循环数;Ct 值;Cycle threshold;循环阈值经过扩增的脱氧核糖核酸探针试样遗传基因;遗传因子;吉恩;生物基因

Example Units

Unit	Source
{Ct_value}	Example UCUM Units

94559-2 SARS-CoV-2 (COVID-19) ORF1ab region [Presence] in Respiratory system specimen by NAA with probe detection

Term Description

Qualitative detection of nucleic acids within the Open Reading Frame 1ab (ORF1ab) region of SARS coronavirus 2 (SARS-CoV-2) in respiratory specimens by nucleic acid amplification with probe-based detection.
Source: Regenstrief LOINC

Reference Information

Type	Source	Reference
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing

Fully-Specified Name

Component: SARS coronavirus 2 ORF1ab region
Property: PrThr
Time: Pt
System: Respiratory System Specimen
Scale: Ord
Method: Probe.amp.tar

Additional Names

Short Name: SARS-CoV-2 ORF1ab Resp Ql NAA+probe
Display Name: SARS-CoV-2 (COVID-19) ORF1ab region NAA+probe Ql (Respiratory system specimen)
Consumer Name Alpha Get Info: SARS-CoV-2 (COVID-19) ORF1ab region, Respiratory system specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.75
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Observation

Example Answer List LL2021-5

Answer	Code	Score	Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6
Invalid Copyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value)			LA15841-2

Member of these Panels

LOINC	Long Common Name
95941-1	Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
92143-7	Respiratory pathogens DNA and RNA panel - Respiratory system specimen by NAA with probe detection
94499-1	Respiratory viral pathogens DNA and RNA panel - Respiratory system specimen Qualitative by NAA with probe detection
96094-8	SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG51017-8	SARSCoV2 detection
LG51019-4	SARSCoV2 molecular detection

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-Coronavirus 2 ORF1ab-Region:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES	Spanish (Spain)	Región ORF1ab del SARS-CoV-2 (COVID-19):PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Sonda con amplificación dirigida Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	Región ORF1ab del coronavirus 2 del SARS:Presencia o umbral:Punto temporal:Espécimen respiratorio:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Coronavirus SARS-CoV-2 région ORF1ab:Présence/Seuil:Ponctuel:Respiratoire:Qualitatif:PCR amplification de cible
fr-CA	French (Canada)	ORF1ab du coronavirus 2 du SRAS:Présence-Seuil:Temps ponctuel:Échantillon du système respiratoire:Ordinal:Sonde avec amplification de la cible
it-IT	Italian (Italy)	SARS coronavirus 2, regione ORF1ab:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar Synonyms: Campione da Apparato Respiratorio Coronavirus della SARS Microbiologia Presenza o Soglia Punto nel tempo (episodio) Regione ORF1ab di SARS-CoV-2 (COVID-19) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-CoV-2 ORF1ab-regio:aanwezigheid:moment:respiratoir monster:ordinaal:probe-detectie Synonyms: probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
zh-CN	Chinese (China)	SARS 冠状病毒 2 ORF1ab 区域:存在情况或阈值:时间点:呼吸系统标本:序数型:探针法.基因扩增.靶向 Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ II SARS 冠状病毒 2 1ab 开放读框区域;2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向区;地区;局部受检物呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间样品样本经过扩增的脱氧核糖核酸探针试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

94644-2 SARS-CoV-2 (COVID-19) ORF1ab region [Cycle Threshold #] in Respiratory system specimen by NAA with probe detection

Term Description

Quantitative detection of nucleic acids within the Open Reading Frame 1ab (ORF1ab) region of SARS coronavirus 2 (SARS-CoV-2) in respiratory specimens by nucleic acid amplification with probe-based detection.
Source: Regenstrief LOINC

Reference Information

Type	Source	Reference
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing

Fully-Specified Name

Component: SARS coronavirus 2 ORF1ab region
Property: ThreshNum
Time: Pt
System: Respiratory System Specimen
Scale: Qn
Method: Probe.amp.tar

Additional Names

Short Name: SARS-CoV-2 ORF1ab Ct Resp Qn NAA+probe
Display Name: SARS-CoV-2 (COVID-19) ORF1ab region NAA+probe (Respiratory system specimen) [ThreshNum]
Consumer Name Alpha Get Info: SARS-CoV-2 (COVID-19) ORF1ab region, Respiratory system specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.75
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
96094-8	SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG51017-8	SARSCoV2 detection
LG51019-4	SARSCoV2 molecular detection

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-Coronavirus 2 ORF1ab-Region:Ct-Wert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Quantitativ:Zielfragmentamplifikation mit Sondendetektion
es-ES	Spanish (Spain)	Región ORF1ab del SARS-CoV-2 (COVID-19):ThreshNnum:Punto temporal:Muestra del sistema respiratorio:Qn:Sonda con amplificación dirigida Synonyms: Cuantitativo Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	Región ORF1ab del coronavirus 2 del SARS:ThreshNum:Punto temporal:Espécimen respiratorio:Cuantitativo:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Coronavirus SARS-CoV-2 région ORF1ab:Cycle seuil:Ponctuel:Respiratoire:Numérique:PCR amplification de cible
it-IT	Italian (Italy)	SARS coronavirus 2, regione ORF1ab:Thresnum:Pt:Campione da Sistema Respiratorio:Qn:Sonda.amp.tar Synonyms: Campione da Apparato Respiratorio Coronavirus della SARS Limite di soglia Microbiologia Punto nel tempo (episodio) Regione ORF1ab di SARS-CoV-2 (COVID-19) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-CoV-2 ORF1ab-regio:drempelwaarde nummer:moment:respiratoir monster:kwantitatief:probe-detectie Synonyms: probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
zh-CN	Chinese (China)	SARS 冠状病毒 2 ORF1ab 区域:阈值循环圈数:时间点:呼吸系统标本:定量型:探针法.基因扩增.靶向 Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ II SARS 冠状病毒 2 1ab 开放读框区域;2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒供检查用的材料;待检物;待试验物;样品;样本;试料;试样借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向区;地区;局部受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间样品样本界值数;界限数;阀值数;临界值数;阈值循环数;阈值数;达到阈值时的循环圈数;荧光信号到达设定阈值时所经历的循环数;Ct 值;Cycle threshold;循环阈值经过扩增的脱氧核糖核酸探针试样

Example Units

Unit	Source
{Ct_value}	Example UCUM Units

94640-0 SARS-CoV-2 (COVID-19) S gene [Presence] in Respiratory system specimen by NAA with probe detection

Term Description

Qualitative detection of nucleic acids within the spike (S) gene of SARS coronavirus 2 (SARS-CoV-2) in respiratory specimens by nucleic acid amplification with probe-based detection.
Source: Regenstrief LOINC

Part Descriptions

LP418046-1 SARS coronavirus 2 S gene
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC: coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] Source: Regenstrief LOINC

Reference Information

Type	Source	Reference
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing

Fully-Specified Name

Component: SARS coronavirus 2 S gene
Property: PrThr
Time: Pt
System: Respiratory System Specimen
Scale: Ord
Method: Probe.amp.tar

Additional Names

Short Name: SARS-CoV-2 S gene Resp Ql NAA+probe
Display Name: SARS-CoV-2 (COVID-19) S gene NAA+probe Ql (Respiratory system specimen)
Consumer Name Alpha Get Info: SARS-CoV-2 (COVID-19) S gene, Respiratory system specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.75
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Both

Example Answer List LL2021-5

Answer	Code	Score	Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6
Invalid Copyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value)			LA15841-2

Member of these Panels

LOINC	Long Common Name
92143-7	Respiratory pathogens DNA and RNA panel - Respiratory system specimen by NAA with probe detection
94499-1	Respiratory viral pathogens DNA and RNA panel - Respiratory system specimen Qualitative by NAA with probe detection
96094-8	SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG51033-5	SARS coronavirus 2 S gene\|PrThr\|Sys:ANYResp
LG51017-8	SARSCoV2 detection
LG51019-4	SARSCoV2 molecular detection

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-Coronavirus 2 S-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES	Spanish (Spain)	Gen S de SARS-CoV-2 (COVID-19):PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Sonda con amplificación dirigida Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	Gen del coronavirus 2 S del SARS:Presencia o umbral:Punto temporal:Espécimen respiratorio:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Coronavirus SARS-CoV-2 gène S:Présence/Seuil:Ponctuel:Respiratoire:Qualitatif:PCR amplification de cible
fr-CA	French (Canada)	gène S du coronavirus 2 du SRAS:Présence-Seuil:Temps ponctuel:Échantillon du système respiratoire:Ordinal:Sonde avec amplification de la cible
it-IT	Italian (Italy)	SARS-CoV-2 (COVID-19), gene S:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar Synonyms: Campione da Apparato Respiratorio Coronavirus della SARS Gene S di SARS-CoV-2 (COVID-19) Microbiologia Presenza o Soglia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-CoV-2 S-gen:aanwezigheid:moment:respiratoir monster:ordinaal:probe-detectie Synonyms: probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
zh-CN	Chinese (China)	SARS 冠状病毒 2 S 基因:存在情况或阈值:时间点:呼吸系统标本:序数型:探针法.基因扩增.靶向 Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ II S 型 SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向受检物呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间样品样本经过扩增的脱氧核糖核酸探针试样遗传基因;遗传因子;吉恩;生物基因

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

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94642-6 SARS-CoV-2 (COVID-19) S gene [Cycle Threshold #] in Respiratory system specimen by NAA with probe detection

Term Description

The quantitative cross/cycle threshold (Ct) value for the detection of nucleic acids within the spike (S) gene of the SARS coronavirus 2 (SARS-CoV-2) in various respiratory specimens by PCR with probe-based detection.
Source: Regenstrief LOINC

Part Descriptions

LP418046-1 SARS coronavirus 2 S gene
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC: coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] Source: Regenstrief LOINC

Reference Information

Type	Source	Reference
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing

Fully-Specified Name

Component: SARS coronavirus 2 S gene
Property: ThreshNum
Time: Pt
System: Respiratory System Specimen
Scale: Qn
Method: Probe.amp.tar

Additional Names

Short Name: SARS-CoV-2 S gene Ct Resp Qn NAA+probe
Display Name: SARS-CoV-2 (COVID-19) S gene NAA+probe (Respiratory system specimen) [ThreshNum]
Consumer Name Alpha Get Info: SARS-CoV-2 (COVID-19) S gene, Respiratory system specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.75
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
96094-8	SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG51017-8	SARSCoV2 detection
LG51019-4	SARSCoV2 molecular detection

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-Coronavirus 2 S-Gen:Ct-Wert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Quantitativ:Zielfragmentamplifikation mit Sondendetektion
es-ES	Spanish (Spain)	Gen S de SARS-CoV-2 (COVID-19):ThreshNnum:Punto temporal:Muestra del sistema respiratorio:Qn:Sonda con amplificación dirigida Synonyms: Cuantitativo Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	Gen del coronavirus 2 S del SARS:ThreshNum:Punto temporal:Espécimen respiratorio:Cuantitativo:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Coronavirus SARS-CoV-2 gène S:Cycle seuil:Ponctuel:Respiratoire:Numérique:PCR amplification de cible
it-IT	Italian (Italy)	SARS-CoV-2 (COVID-19), gene S:Thresnum:Pt:Campione da Sistema Respiratorio:Qn:Sonda.amp.tar Synonyms: Campione da Apparato Respiratorio Coronavirus della SARS Gene S di SARS-CoV-2 (COVID-19) Limite di soglia Microbiologia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-CoV-2 S-gen:drempelwaarde nummer:moment:respiratoir monster:kwantitatief:probe-detectie Synonyms: probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
zh-CN	Chinese (China)	SARS 冠状病毒 2 S 基因:阈值循环圈数:时间点:呼吸系统标本:定量型:探针法.基因扩增.靶向 Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ II S 型 SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒供检查用的材料;待检物;待试验物;样品;样本;试料;试样借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向受检物可用数量表示的;定量性;数值型;数量型;连续数值型标尺呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间样品样本界值数;界限数;阀值数;临界值数;阈值循环数;阈值数;达到阈值时的循环圈数;荧光信号到达设定阈值时所经历的循环数;Ct 值;Cycle threshold;循环阈值经过扩增的脱氧核糖核酸探针试样遗传基因;遗传因子;吉恩;生物基因

Example Units

Unit	Source
{Ct_value}	Example UCUM Units

94758-0 SARS-related coronavirus E gene [Presence] in Respiratory system specimen by NAA with probe detection

Term Description

Qualitative detection of nucleic acids within the envelope (E) gene of SARS-related coronavirus in respiratory specimens by nucleic acid amplification with probe-based detection.
Source: Regenstrief LOINC

Part Descriptions

LP417600-6 SARS-related coronavirus E gene
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC: coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] Source: Regenstrief LOINC

Reference Information

Type	Source	Reference
Mapping Guidance	LOINC	Take caution when mapping LOINC codes to molecular tests for SARS coronaviruses that target nucleic acids within the E gene. Such assays detect either SARS-related coronavirus or SARS-CoV-2, depending on the targeted region within the E gene. Assays that are non-specific to only SARS-CoV-2 may say they are "positive" for SARS-CoV-2, but only because it is the primary circulating virus during the pandemic. These assays actually detect any SARS-related coronaviruses since they target a region in the E gene that contains sequence homology to other known coronaviruses. Other assays target a region in the E gene that is specific for SARS-CoV-2. The LIVD file contains current LOINC code mappings to many IVD tests [https://www.cdc.gov/csels/dls/sars-cov-2-livd-codes.html]. You may also contact the manufacturer directly to verify LOINC code mappings.
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing

Fully-Specified Name

Component: SARS-related coronavirus E gene
Property: PrThr
Time: Pt
System: Respiratory System Specimen
Scale: Ord
Method: Probe.amp.tar

Additional Names

Short Name: SARS-rel CoV E gene Resp Ql NAA+probe
Display Name: SARS-related coronavirus E gene NAA+probe Ql (Respiratory system specimen)
Consumer Name Alpha Get Info: SARS-related coronavirus E gene, Respiratory system specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.75
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Observation

Example Answer List LL744-4

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Member of these Panels

LOINC	Long Common Name
96094-8	SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG50982-4	SARS-related coronavirus
LG51048-3	SARS-related coronavirus E gene\|PrThr\|Sys:ANYResp

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-bezogenes Coronavirus E-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES	Spanish (Spain)	Gen del coronavirus E relacionado con el SARS:PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Sonda con amplificación dirigida Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	Gen del coronavirus E relacionado con el SARS:Presencia o umbral:Punto temporal:Espécimen respiratorio:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Coronavirus SARS apparentés gène E:Présence/Seuil:Ponctuel:Respiratoire:Qualitatif:PCR amplification de cible
fr-CA	French (Canada)	gène E du coronavirus 2 du SRAS:Présence-Seuil:Temps ponctuel:Échantillon du système respiratoire:Ordinal:Sonde avec amplification de la cible
it-IT	Italian (Italy)	Coronavirus correlato a SARS, gene E:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar Synonyms: Campione da Apparato Respiratorio Gene E di coronavirus correlato a SARS Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-gerelateerd coronavirus E-gen:aanwezigheid:moment:respiratoir monster:ordinaal:probe-detectie Synonyms: probe.amp.tar systema respiratorium; ademhalingsstelsel
zh-CN	Chinese (China)	SARS 冠状病毒 2 E 基因:存在情况或阈值:时间点:呼吸系统标本:序数型:探针法.基因扩增.靶向 Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 E 型严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向受检物呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间样品样本经过扩增的脱氧核糖核酸探针试样遗传基因;遗传因子;吉恩;生物基因

94502-2 SARS-related coronavirus RNA [Presence] in Respiratory system specimen by NAA with probe detection

Term Description

Qualitative detection targeted nucleic acids from SARS-related coronavirus RNA, including SARS coronavirus (SARS-CoV), SARS coronavirus 2 (SARS-CoV-2), and SARS-like coronaviruses, in upper or lower respiratory specimens. This test detects but does not differentiate between the viruses.
Source: Regenstrief LOINC

Fully-Specified Name

Component: SARS-related coronavirus RNA
Property: PrThr
Time: Pt
System: Respiratory System Specimen
Scale: Ord
Method: Probe.amp.tar

Additional Names

Short Name: SARS-rel CoV RNA Resp Ql NAA+probe
Display Name: SARS-related CoV RNA NAA+probe Ql (Respiratory system specimen)
Consumer Name Alpha Get Info: SARS-related coronavirus, Respiratory system specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.75
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Both

Example Answer List LL360-9

Answer	Code	Score	Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Member of these Panels

LOINC	Long Common Name
95380-2	Influenza virus A and B and SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
92143-7	Respiratory pathogens DNA and RNA panel - Respiratory system specimen by NAA with probe detection
94499-1	Respiratory viral pathogens DNA and RNA panel - Respiratory system specimen Qualitative by NAA with probe detection
96094-8	SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG50982-4	SARS-related coronavirus

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-bezogenes Coronavirus RNA:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES	Spanish (Spain)	Coronavirus relacionado con el SARS RNA:PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Sonda con amplificación dirigida Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	ARN del coronavirus relacionado con el SARS:Presencia o umbral:Punto temporal:Espécimen respiratorio:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-CA	French (Canada)	ARN du coronavirus lié au SRAS , ARN:Présence-Seuil:Temps ponctuel:Échantillon du système respiratoire:Ordinal:Sonde avec amplification de la cible
fr-FR	French (France)	Coronavirus SARS apparentés ARN:Présence/Seuil:Ponctuel:Respiratoire:Qualitatif:PCR amplification de cible
it-IT	Italian (Italy)	Coronavirus correlato a SARS RNA:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar Synonyms: Campione da Apparato Respiratorio Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-gerelateerd coronavirus RNA:aanwezigheid:moment:respiratoir monster:ordinaal:probe-detectie Synonyms: probe.amp.tar systema respiratorium; ademhalingsstelsel
zh-CN	Chinese (China)	SARS-相关冠状病毒 RNA:存在情况或阈值:时间点:呼吸系统标本:序数型:探针法.基因扩增.靶向 Synonyms: 严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向受检物呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间样品样本核糖核酸;Ribonucleic acid 经过扩增的脱氧核糖核酸探针试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

94532-9 SARS-related coronavirus+MERS coronavirus RNA [Presence] in Respiratory system specimen by NAA with probe detection

Term Description

Qualitative detection of targeted nucleic acids from SARS-related coronaviruses, including SARS coronavirus (SARS-CoV), SARS coronavirus 2 (SARS-CoV-2), and SARS-like coronaviruses, as well as MERS coronavirus RNA in respiratory specimens. This test detects but does not differentiate between the viruses.
Source: Regenstrief LOINC

Fully-Specified Name

Component: SARS-related coronavirus+MERS coronavirus RNA
Property: PrThr
Time: Pt
System: Respiratory System Specimen
Scale: Ord
Method: Probe.amp.tar

Additional Names

Short Name: SARS-rel CoV+MERS RNA Resp Ql NAA+probe
Display Name: SARS-related CoV+MERS coronavirus RNA NAA+probe Ql (Respiratory system specimen)
Consumer Name Alpha Get Info: SARS-related coronavirus+MERS coronavirus, Respiratory system specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.75
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Observation

Example Answer List LL2021-5

Answer	Code	Score	Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6
Invalid Copyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value)			LA15841-2

Member of these Panels

LOINC	Long Common Name
92143-7	Respiratory pathogens DNA and RNA panel - Respiratory system specimen by NAA with probe detection
94499-1	Respiratory viral pathogens DNA and RNA panel - Respiratory system specimen Qualitative by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG50982-4	SARS-related coronavirus

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-bezogenes Coronavirus+MERS Coronavirus RNA:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES	Spanish (Spain)	Coronavirus relacionado con el SARS + coronavirus MERS RNA:PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Sonda con amplificación dirigida Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	Coronavirus relacionado con el SARS + ARN del coronavirus MERS:Presencia o umbral:Punto temporal:Espécimen respiratorio:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Coronavirus SARS apparentés+coronavirus MERS ARN:Présence/Seuil:Ponctuel:Respiratoire:Qualitatif:PCR amplification de cible
it-IT	Italian (Italy)	Coronavirus correlato a SARS+coronavirus MERS RNA:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar Synonyms: Campione da Apparato Respiratorio Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-gerelateerd coronavirus + MERS-coronavirus RNA:aanwezigheid:moment:respiratoir monster:ordinaal:probe-detectie Synonyms: probe.amp.tar systema respiratorium; ademhalingsstelsel
zh-CN	Chinese (China)	SARS-相关冠状病毒+MERS 冠状病毒 RNA:存在情况或阈值:时间点:呼吸系统标本:序数型:探针法.基因扩增.靶向 Synonyms: 严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典中东呼吸综合征冠状病毒;Middle East Respiratory Syndrome Coronavirus;MERS-CoV;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向受检物呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间样品样本核糖核酸;Ribonucleic acid 经过扩增的脱氧核糖核酸探针试样

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

97104-4 SARS-CoV-2 (COVID-19) ORF1ab region [Units/volume] (viral load) in Upper respiratory specimen by NAA with probe detection

Term Description

Quantitative detection of nucleic acids within the Open Reading Frame 1ab (ORF1ab) region of SARS coronavirus 2 (SARS-CoV-2) in upper respiratory specimens by nucleic acid amplification with probe-based detection.
Source: Regenstrief LOINC

Reference Information

Type	Source	Reference
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing

Fully-Specified Name

Component: SARS coronavirus 2 ORF1ab region
Property: ACnc
Time: Pt
System: Respiratory system specimen.upper
Scale: Qn
Method: Probe.amp.tar

Additional Names

Short Name: SARS-CoV-2 ORF1ab U resp NAA+probe-aCnc
Display Name: SARS-CoV-2 (COVID-19) ORF1ab region NAA+probe Qn (Upper resp)
Consumer Name Alpha Get Info: SARS-CoV-2 (COVID-19) ORF1ab region, Upper respiratory

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.70
Last Updated: Version 2.77
Change Reason: Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
101721-9	Deprecated SARS-CoV-2 (COVID-19) in Respiratory specimen by NAA with probe detection
103202-8	Deprecated SARS-CoV-2 (COVID-19) RNA in Respiratory specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG51017-8	SARSCoV2 detection
LG51019-4	SARSCoV2 molecular detection

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-Coronavirus 2 ORF1ab-Region:Arbiträre Konzentration:Zeitpunkt:Probenmaterial vom oberen Respirationstrakt:Quantitativ:Zielfragmentamplifikation mit Sondendetektion
es-MX	Spanish (Mexico)	Región ORF1ab del coronavirus 2 del SARS:ACnc:Punto temporal:Respiratorio superior:Cuantitativo:Probe.amp.tar
fr-FR	French (France)	Coronavirus SARS-CoV-2 région ORF1ab:Arbitraire/Volume:Ponctuel:Voies respiratoires supérieures:Numérique:PCR amplification de cible
nl-NL	Dutch (Netherlands)	SARS-CoV-2 ORF1ab-regio:eenheid/volume:moment:bovenste luchtwegen:kwantitatief:probe-detectie Synonyms: bovenste ademhalingsstelsel; systema respiratorium superior probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel

Example Units

Unit	Source
[IU]/mL	Example UCUM Units

94531-1

SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Active

94500-6 SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

Term Description

Part Descriptions

Reference Information

Fully-Specified Name

Additional Names

Basic Attributes

Example Answer List LL2021-5

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Related Names

Third Party Copyright

94745-7 SARS-CoV-2 (COVID-19) RNA [Cycle Threshold #] in Respiratory system specimen by NAA with probe detection

Part Descriptions

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Example Units

96763-8 SARS-CoV-2 (COVID-19) E gene [Presence] in Respiratory system specimen by NAA with probe detection

Term Description

Reference Information

Fully-Specified Name

Additional Names

Basic Attributes

Example Answer List LL360-9

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Related Names

Third Party Copyright

96764-6 SARS-CoV-2 (COVID-19) E gene [Cycle Threshold #] in Respiratory system specimen by NAA with probe detection

Term Description

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Example Units

94533-7 SARS-CoV-2 (COVID-19) N gene [Presence] in Respiratory system specimen by NAA with probe detection

Term Description

Part Descriptions

Reference Information

Fully-Specified Name

Additional Names

Basic Attributes

Example Answer List LL2009-0

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Third Party Copyright

94757-2 SARS-CoV-2 (COVID-19) N gene [Presence] in Respiratory system specimen by Nucleic acid amplification using CDC primer-probe set N2

Term Description

Part Descriptions

Reference Information

Fully-Specified Name

Additional Names

Basic Attributes

Example Answer List LL744-4

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Related Names

94756-4 SARS-CoV-2 (COVID-19) N gene [Presence] in Respiratory system specimen by Nucleic acid amplification using CDC primer-probe set N1

Term Description

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Fully-Specified Name