Version 2.77

92142-9 Influenza virus A RNA [Presence] in Respiratory system specimen by NAA with probe detection

Part Descriptions

LP14239-5   Influenza virus A
Influenza viruses, from the family Orthomyxoviridae, are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C are medically relevant to humans. Aquatic birds harboring avian IAV are the likely natural reservoir for all known IAV subtypes and are probably the original source of all human pandemic IAV strains. IAV maintained in wild birds have been associated with stable host switch events to novel hosts, including most often to domestic poultry but also to horses, swine, toothed whales and humans. The influenza virus life cycle begins with the binding of viral HA to host cell receptors. Endocytosis and HA-mediated fusion of the viral and cellular membranes occurs. Viral ribonucleoprotein complexes are released into the cytoplasm, travel to the nucleus, then are replicated and transcribed by the viral polymerase complex. The new viruses are formed and bud when the newly formed ribonucleicprotein complexes and structural proteins reach the plasma membrane. Further research is needed to better understand how IAVs switch hosts and the viral genetic changes that underlie human adaptation. IAV causes respiratory infections in humans ranging from asymptomatic to fatal. Pandemics are attributed to "novel" viruses which possess a viral hemagglutinin (HA) to which humans do not have immunity. PMID: 20542248 ] PMID: 25812763
Influenza viruses A and B are single-stranded RNA enveloped viruses belonging to the Orthomyxoviridae family. The symptoms of infection of Influenza A and B include fever, cough, sore throat, rhinorrhea, nasal congestion, headache, myalgia and malaise. Some patients may experience gastrointestinal symptoms including watery diarrhea, vomiting and abdominal pain. The influenza viruses spread rapidly in enclosed spaces with a documented rate of infection of 70% following a common source of exposure. Infection occurs in the respiratory epithelium in both the upper and lower respiratory tract, and the virus can be found in many specimen types, including nasal aspirates, nasal or nasopharyngeal swabs, throat swabs, sputum and tracheal aspirates. When infection rates reach epidemic proportions, hospitalization of children and elderly patients rises as does the mortality rates of elderly patients.(Manual of Clinical Microbiology, 11th edition, James H. Jorgensen; Karen C. Carroll; Guido Funke; Michael A Pfaller; Marie Louise Landry; Sandra S. Richter; David W. Warnock) Source: Regenstrief LOINC

Fully-Specified Name

Component
Influenza virus A RNA
Property
PrThr
Time
Pt
System
Respiratory System Specimen
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
FLUAV RNA Resp Ql NAA+probe
Display Name
FLUAV RNA NAA+probe Ql (Respiratory system specimen)
Consumer Name Alpha Get Info
Influenza A (Flu A), Respiratory system specimen

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.66
Last Updated
Version 2.75
Change Reason
Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation
Both

Example Answer List LL360-9

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
95941-1 Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
95380-2 Influenza virus A and B and SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
95422-2 Influenza virus A and B and SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection
92143-7 Respiratory pathogens DNA and RNA panel - Respiratory system specimen by NAA with probe detection
94499-1 Respiratory viral pathogens DNA and RNA panel - Respiratory system specimen Qualitative by NAA with probe detection

Member of these Groups Get Info

LOINC Group Group Name
LG32757-3 Influenza virus
LG34064-2 Influenza virus A RNA|PrThr|Sys:ANYResp

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Influenza-Virus A RNA:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-MX Spanish (Mexico) ARN del virus de la influenza A:Presencia o umbral:Punto temporal:Espécimen respiratorio:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
es-ES Spanish (Spain) Virus Influenza A RNA:PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Sonda con amplificación dirigida
Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
fr-FR French (France) Influenza virus A ARN:Présence/Seuil:Ponctuel:Respiratoire:Qualitatif:PCR amplification de cible
fr-CA French (Canada) Virus de l'influenza A , ARN:Présence-Seuil:Temps ponctuel:Échantillon du système respiratoire:Ordinal:Sonde avec amplification de la cible
it-IT Italian (Italy) Influenza A, virus RNA:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar
Synonyms: Campione da Apparato Respiratorio Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''influenza Virus dell''influenza A
nl-NL Dutch (Netherlands) Influenzavirus A RNA:aanwezigheid:moment:respiratoir monster:ordinaal:probe-detectie
Synonyms: probe.amp.tar systema respiratorium; ademhalingsstelsel
zh-CN Chinese (China) 流感病毒 A 型 RNA:存在情况或阈值:时间点:呼吸系统标本:序数型:探针法.基因扩增.靶向
Synonyms: A 型 A 型流感;A 型流感病毒;FLUA;FLUAV;家禽鼠疫;流感 A;流感 A 型;流感甲型;流感病毒甲型;甲型流感;甲型流感病毒;瘟疫;禽流感;禽流行性感冒;禽疫;鸡瘟 A 型流感病毒 RNA FLUA RNA FLUAV RNA FLUV;Influ;列性感冒病毒;流行性感冒病毒 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 受检物 呼吸道标本（样品、样本）;呼吸系统标本（样品、样本） 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 样品 样本 核糖核酸;Ribonucleic acid 流感病毒甲型 RNA 甲型流感病毒 RNA 经过扩增的 脱氧核糖核酸探针 试样

92141-1 Influenza virus B RNA [Presence] in Respiratory system specimen by NAA with probe detection

Part Descriptions

LP14240-3   Influenza virus B
Influenza virus from the family Orthomyxoviridae are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C viruses are medically relevant to humans. Influenza A and B viruses have a similar structure whereby these viruses each contain eight discrete single-stranded RNA gene segments, each encoding at least one protein. While having a close phylogenetic relationship, influenza virus types A and B manifest very differently. While IAV infects birds, humans and other mammals, influenza B only infects humans and seals. Although both viruses cause human respiratory infection seasonally in temperate climate regions and more continually in the tropics, influenza B is normally less prevalent and causes less severe disease than IAV viruses. Research is ongoing to determine the evolutionary and epidemiological factors that shape the genetic diversity of influenza B virus. PMID: 25812763 [CDC:flu/about/viruses/types] Source: Regenstrief LOINC

Fully-Specified Name

Component
Influenza virus B RNA
Property
PrThr
Time
Pt
System
Respiratory System Specimen
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
FLUBV RNA Resp Ql NAA+probe
Display Name
FLUBV RNA NAA+probe Ql (Respiratory system specimen)
Consumer Name Alpha Get Info
Influenza B (Flu B), Respiratory system specimen

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.66
Last Updated
Version 2.75
Change Reason
Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation
Both

Example Answer List LL360-9

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
95941-1 Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
95380-2 Influenza virus A and B and SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
95422-2 Influenza virus A and B and SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection
92143-7 Respiratory pathogens DNA and RNA panel - Respiratory system specimen by NAA with probe detection
94499-1 Respiratory viral pathogens DNA and RNA panel - Respiratory system specimen Qualitative by NAA with probe detection

Member of these Groups Get Info

LOINC Group Group Name
LG32757-3 Influenza virus
LG34065-9 Influenza virus B RNA|PrThr|Sys:ANYResp

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Influenza-Virus B RNA:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-MX Spanish (Mexico) ARN del virus de la influenza B:Presencia o umbral:Punto temporal:Espécimen respiratorio:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
es-ES Spanish (Spain) Virus Influenza B RNA:PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Sonda con amplificación dirigida
Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
fr-CA French (Canada) Virus de l'influenza B , ARN:Présence-Seuil:Temps ponctuel:Échantillon du système respiratoire:Ordinal:Sonde avec amplification de la cible
fr-FR French (France) Influenza virus B ARN:Présence/Seuil:Ponctuel:Respiratoire:Qualitatif:PCR amplification de cible
it-IT Italian (Italy) Influenza B, virus RNA:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar
Synonyms: Campione da Apparato Respiratorio Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''influenza Virus dell''influenza B
nl-NL Dutch (Netherlands) Influenzavirus B RNA:aanwezigheid:moment:respiratoir monster:ordinaal:probe-detectie
Synonyms: probe.amp.tar systema respiratorium; ademhalingsstelsel
zh-CN Chinese (China) 流感病毒 B 型 RNA:存在情况或阈值:时间点:呼吸系统标本:序数型:探针法.基因扩增.靶向
Synonyms: B 型 B 型流感;B 型流感病毒;FLUB;FLUBV;乙型流感;乙型流感病毒;流感 B;流感 B 型;流感乙型;流感病毒乙型 B 型流感病毒 RNA FLUB RNA FLUBV RNA FLUV;Influ;列性感冒病毒;流行性感冒病毒 乙型流感病毒 RNA 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 受检物 呼吸道标本（样品、样本）;呼吸系统标本（样品、样本） 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 样品 样本 核糖核酸;Ribonucleic acid 流感病毒乙型 RNA 经过扩增的 脱氧核糖核酸探针 试样

94533-7 SARS-CoV-2 (COVID-19) N gene [Presence] in Respiratory system specimen by NAA with probe detection

Term Description

Qualitative detection of nucleic acids within the nucleoprotein (N) gene of SARS coronavirus 2 (SARS-CoV-2) in respiratory specimens by nucleic acid amplification with probe-based detection. Various assays have been developed that contain primer-probe sets targeting N gene. [https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance]
Source: Regenstrief LOINC

Part Descriptions

LP417599-0   SARS coronavirus 2 N gene
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC: coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] Source: Regenstrief LOINC

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Coronavirus (COVID-19) Testing

Fully-Specified Name

Component
SARS coronavirus 2 N gene
Property
PrThr
Time
Pt
System
Respiratory System Specimen
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
SARS-CoV-2 N gene Resp Ql NAA+probe
Display Name
SARS-CoV-2 (COVID-19) N gene NAA+probe Ql (Respiratory system specimen)
Consumer Name Alpha Get Info
SARS-CoV-2 (COVID-19) N gene, Respiratory system specimen

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.75
Change Reason
Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation
Both

Example Answer List LL2009-0

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6
Equivocal Copyright http://snomed.info/sct ID:42425007 Equivocal (qualifier value) LA11885-3

Member of these Panels

LOINC Long Common Name
95941-1 Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
95422-2 Influenza virus A and B and SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection
92143-7 Respiratory pathogens DNA and RNA panel - Respiratory system specimen by NAA with probe detection
94499-1 Respiratory viral pathogens DNA and RNA panel - Respiratory system specimen Qualitative by NAA with probe detection
96094-8 SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1 SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group Group Name
LG51004-6 SARS coronavirus 2 N gene|PrThr|Sys:ANYResp
LG51017-8 SARSCoV2 detection
LG51019-4 SARSCoV2 molecular detection

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) SARS-Coronavirus 2 N-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-MX Spanish (Mexico) Gen del coronavirus 2 N del SARS:Presencia o umbral:Punto temporal:Espécimen respiratorio:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
es-ES Spanish (Spain) Gen N de SARS-CoV-2 (COVID-19):PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Sonda con amplificación dirigida
Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
fr-CA French (Canada) gène N du coronavirus 2  du SRAS:Présence-Seuil:Temps ponctuel:Échantillon du système respiratoire:Ordinal:Sonde avec amplification de la cible
fr-FR French (France) Coronavirus SARS-CoV-2 gène N:Présence/Seuil:Ponctuel:Respiratoire:Qualitatif:PCR amplification de cible
it-IT Italian (Italy) SARS coronavirus 2, gene N:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar
Synonyms: Campione da Apparato Respiratorio Coronavirus della SARS Gene N di SARS-CoV-2 (COVID-19) Microbiologia Presenza o Soglia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL Dutch (Netherlands) SARS-CoV-2 N-gen:aanwezigheid:moment:respiratoir monster:ordinaal:probe-detectie
Synonyms: evere acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
zh-CN Chinese (China) SARS 冠状病毒 2 N 基因:存在情况或阈值:时间点:呼吸系统标本:序数型:探针法.基因扩增.靶向
Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ II N 型 SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 受检物 呼吸道标本（样品、样本）;呼吸系统标本（样品、样本） 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 样品 样本 经过扩增的 脱氧核糖核酸探针 试样 遗传基因;遗传因子;吉恩;生物基因

94500-6 SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

Term Description

Qualitative detection of SARS coronavirus 2 (SARS-CoV-2) in respiratory specimens by nucleic acid amplification with probe-based detection. Results may be based on multiple assays to determine the presence of the virus in a specimen.
Source: Regenstrief LOINC

Part Descriptions

LP417540-4   SARS coronavirus 2
The 2019 Novel Coronavirus (2019-nCoV) is a coronavirus first identified as the cause of a respiratory illness outbreak in Wuhan, China. Initially, the outbreak was linked to a large seafood and animal market and thought to only be spread by animal to person contact. Within a short time, a growing number of patients who had not been exposed to animal markets were diagnosed with the infection, indicating person-to-person transmission. As of January 2020, infections with 2019-nCoV had been reported internationally due to confirmed cases in travelers from Wuhan. Overall, clinical symptoms appear milder than SARS Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome (MERS) Coronavirus (MERS-CoV) infections as do the fatality rate and transmissibility. PMID: 31953166 Reported illnesses range from minor or no respiratory symptoms to severe acute respiratory illness and death.

The full genome of the 2019-nCoV was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Source: LOINC

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Coronavirus (COVID-19) Testing

Fully-Specified Name

Component
SARS coronavirus 2 RNA
Property
PrThr
Time
Pt
System
Respiratory System Specimen
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
SARS-CoV-2 RNA Resp Ql NAA+probe
Display Name
SARS-CoV-2 (COVID-19) RNA NAA+probe Ql (Respiratory system specimen)
Consumer Name Alpha Get Info
SARS-CoV-2 (COVID-19), Respiratory system specimen

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.75
Change Reason
Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation
Both
Common Test Rank Get Info
65

Example Answer List LL2021-5

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6
Invalid Copyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value) LA15841-2

Member of these Panels

LOINC Long Common Name
101721-9 Deprecated SARS-CoV-2 (COVID-19) in Respiratory specimen by NAA with probe detection
103202-8 Deprecated SARS-CoV-2 (COVID-19) RNA in Respiratory specimen by NAA with probe detection
95941-1 Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
95380-2 Influenza virus A and B and SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
95422-2 Influenza virus A and B and SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection
92143-7 Respiratory pathogens DNA and RNA panel - Respiratory system specimen by NAA with probe detection
94499-1 Respiratory viral pathogens DNA and RNA panel - Respiratory system specimen Qualitative by NAA with probe detection
96094-8 SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1 SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group Group Name
LG50983-2 SARS coronavirus 2 RNA|PrThr|Sys:ANYResp
LG51017-8 SARSCoV2 detection
LG51019-4 SARSCoV2 molecular detection

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) SARS-Coronavirus 2 RNA:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion
de-AT German (Austria) Synonyms: SCV2-RNA ql. /RT P
es-MX Spanish (Mexico) ARN del coronavirus 2 del SARS:Presencia o umbral:Punto temporal:Espécimen respiratorio:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
es-ES Spanish (Spain) Panel del SARS-CoV-2 (COVID-19) RNA:PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Sonda con amplificación dirigida
Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
fr-FR French (France) Coronavirus SARS-CoV-2 ARN:Présence/Seuil:Ponctuel:Respiratoire:Qualitatif:PCR amplification de cible
fr-CA French (Canada) coronavirus 2 du SRAS , ARN:Présence-Seuil:Temps ponctuel:Échantillon du système respiratoire:Ordinal:Sonde avec amplification de la cible
it-IT Italian (Italy) SARS coronavirus 2 RNA:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar
Synonyms: Campione da Apparato Respiratorio Coronavirus della SARS Microbiologia Presenza o Soglia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL Dutch (Netherlands) SARS-CoV-2 RNA:aanwezigheid:moment:respiratoir monster:ordinaal:probe-detectie
Synonyms: probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
uk-UA Ukrainian (Ukraine) SARS коронавірус 2 РНК:Наявність або Поріг:МоментЧасу:Респіраторний зразок:Порядково:Зонд-детекція. цільова аміпліфікація НК
Synonyms: 2019 Novel Coronavirus; 2019-nCoV; 3 Self-Sustaining Sequence Replication; 3SR SR; Amplif; Amplification; Amplified; Corona virus; COVID19; COVID-19; DNA NUCLEIC ACID PROBE; DNA probe; ID; II; Infectious Disease; InfectiousDisease; LAT; LCR; Ligase chain reaction; Ligation-activated transcription; Microbiology; NAA+probe; NAAT; NASBA; Nucleic acid sequence based analysis; Ordinal; PCR; Point in time; Polymerase chain reaction; PR; Probe amp; Probe with ampification; Probe with target amplification; QBR; QL; Qual; Qualitative; Random; Ribonucleic acid; SARS Coronavirus 1; SARS-CoV; SARS-CoV-1; SARS-CoV-2; Screen; SDA; Severe Acute Respiratory Syndrome; Strand Displacement Amplification; TMA; Transcription mediated amplification; Viral Pneumonias; Wuhan coronavirus
zh-CN Chinese (China) SARS 冠状病毒 2 RNA:存在情况或阈值:时间点:呼吸系统标本:序数型:探针法.基因扩增.靶向
Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ II SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 受检物 呼吸道标本（样品、样本）;呼吸系统标本（样品、样本） 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 样品 样本 核糖核酸;Ribonucleic acid 经过扩增的 脱氧核糖核酸探针 试样

68993-5 Human RNase P RNA [Presence] in Specimen by NAA with probe detection

Term Description

Used as a control for determination of adequate human cells in clinical samples for viral testing
Source: Regenstrief LOINC

Part Descriptions

LP135667-6   Human RNase P
Ribonuclease P (EC 3.1.26.5, RNase P) is a type of ribonuclease which cleaves RNA. RNase P is unique from other RNases in that it is a ribozyme - a ribonucleic acid that acts as a catalyst in the same way that a protein based enzyme would. Its function is to cleave off an extra, or precursor, sequence of RNA on tRNA molecules. Further, RNase P is one of two known multiple turnover ribozymes in nature (the other being the ribosome), the discovery of which earned Sidney Altman and Thomas Cech the Nobel Prize in Chemistry in 1989: in the 1970s, Altman discovered the existence of precursor tRNA with flanking sequences and was the first to characterize RNase P and its activity in processing of the 5' leader sequence of precursor tRNA. Recent findings also reveal that RNase P has a new function. It has been shown that human nuclear RNase P is required for the normal and efficient transcription of various small noncoding RNAs, such as tRNA, 5S rRNA, SRP RNA and U6 snRNA genes., which are transcribed by RNA polymerase III, one of three major nuclear RNA polymerases in human cells. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Fully-Specified Name

Component
Human RNase P RNA
Property
PrThr
Time
Pt
System
XXX
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
Human RNase P RNA Spec Ql NAA+probe
Display Name
Human RNase P RNA NAA+probe Ql (Specimen)
Consumer Name Alpha Get Info
Human RNase P, Specimen

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.38
Last Updated
Version 2.69
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Observation

Example Answer List LL744-4

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Member of these Panels

LOINC Long Common Name
95422-2 Influenza virus A and B and SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection
101398-6 Monkeypox virus and Orthopoxvirus.non-variola DNA panel - Specimen

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Humane RNase P RNA:Nachweis oder Schwellenwert:Zeitpunkt:XXX:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-MX Spanish (Mexico) ARN Rnasa P humana:Presencia o umbral:Punto temporal:XXX:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
es-ES Spanish (Spain) Rnase P humana RNA:PrThr:Punto temporal:XXX:Ord:Sonda con amplificación dirigida
fr-FR French (France) Ribonucléase P ARN:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:PCR amplification de cible
it-IT Italian (Italy) Rnasi P umana RNA:PrThr:Pt:XXX:Ord:Sonda.amp.tar
Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL Dutch (Netherlands) Humaan Rnase P RNA:aanwezigheid:moment:XXX:ordinaal:probe-detectie
Synonyms: probe.amp.tar
ru-RU Russian (Russian Federation) Человеческая РНКаза P РНК:PrThr:ТчкВрм:XXX:Пор:Проба.усил.миш
Synonyms: ДНК проба;ДНК зонд Порядковый Проба с мишени усилением Точка во времени;Момент
tr-TR Turkish (Turkey) Human Rnaz P RNA:MevcEşik:Zmlı:XXX:Srl:Prob.amf.hdf
Synonyms: Mevcut
zh-CN Chinese (China) 人核糖核酸酶 P RNA:存在情况或阈值:时间点:XXX:序数型:探针法.基因扩增.靶向
Synonyms: P 型 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 人核酶 P;人 RNA P 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 核糖核酸;Ribonucleic acid 经过扩增的 脱氧核糖核酸探针

95423-0 Influenza virus A and B and SARS-CoV-2 (COVID-19) identified in Respiratory system specimen by NAA with probe detection

Term Description

Detection and identification of SARS-CoV-2 (COVID-19), Influenza virus A, and/or Influenza virus B in respiratory specimens by nucleic acid amplification with probe-based detection.
Source: Regenstrief LOINC

Fully-Specified Name

Component
Influenza virus A & Influenza virus B & SARS coronavirus 2 identified
Property
Prid
Time
Pt
System
Respiratory System Specimen
Scale
Nom
Method
Probe.amp.tar

Additional Names

Short Name
FLUABV + SARS-CoV-2 Resp NAA+probe
Display Name
Influenza virus A and B and SARS-CoV-2 (COVID-19) identified NAA+probe Nom (Respiratory system specimen)
Consumer Name Alpha Get Info
Influenza virus A and B and SARS-CoV-2 (COVID-19) test, Respiratory system specimen

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.69
Last Updated
Version 2.75
Change Reason
Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation
Observation

Example Answer List LL5604-5

Answer Code Score Answer ID
Influenza A virus Copyright http://snomed.info/sct ID:407479009 Influenza A virus (organism) LA11919-0
Influenza B virus Copyright http://snomed.info/sct ID:407480007 Influenza B virus (organism) LA13543-6
SARS coronavirus 2 Copyright http://snomed.info/sct ID:840533007 Severe acute respiratory syndrome coronavirus 2 (organism) LA31065-8
Not detected LA11883-8
Specimen unsatisfactory for evaluation Copyright http://snomed.info/sct ID:125154007 Specimen unsatisfactory for evaluation (finding) LA13548-5
Invalid Copyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value) LA15841-2

Member of these Panels

LOINC Long Common Name
95422-2 Influenza virus A and B and SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group Group Name
LG32757-3 Influenza virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Influenza-Virus A & Influenza-Virus B & SARS Coronavirus 2 identifiziert:Nachweis oder Identität:Zeitpunkt:Probenmaterial vom Respirationstrakt:Nominal:Zielfragmentamplifikation mit Sondendetektion
es-MX Spanish (Mexico) Virus de influenza A y B y SARS-CoV-2 (COVID-19) identificados:Presencia o identidad:Punto temporal:Espécimen respiratorio:Nominal:Amplificación de ácidos nucleicos con detección de sonda
es-ES Spanish (Spain) Virus de la influenza A y B y SARS-CoV-2 (COVID-19) identificado:Presencia o identidad:Punto temporal:Muestra del sistema respiratorio:Nom:Sonda con amplificación dirigida
Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
fr-FR French (France) Influenza virus A et B et Coronavirus SARS-Cov-2 identifié:Identification:Ponctuel:Respiratoire:Résultat nominal:PCR amplification de cible
it-IT Italian (Italy) Influenza virus A & Influenza virus B & SARS coronavirus 2 , identificato:Prid:Pt:Campione da Sistema Respiratorio:Nom:Sonda.amp.tar
Synonyms: Campione da Apparato Respiratorio Coronavirus della SARS Microbiologia Presenza o Identità Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''influenza Virus dell''influenza A Virus dell''influenza B
nl-NL Dutch (Netherlands) influenzavirus A & influenzavirus B & SARS-CoV-2 geïdentificeerd:identificator:moment:respiratoir monster:nominaal:probe-detectie
Synonyms: probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
zh-CN Chinese (China) 流感病毒 A & 流感病毒 B & SARS 冠状病毒 2 已鉴定的:存在与否或特征标识:时间点:呼吸系统标本:名义型:探针法.基因扩增.靶向
Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ A 型 A 型流感;A 型流感病毒;FLUA;FLUAV;家禽鼠疫;流感 A;流感 A 型;流感甲型;流感病毒甲型;甲型流感;甲型流感病毒;瘟疫;禽流感;禽流行性感冒;禽疫;鸡瘟 B 型 B 型流感;B 型流感病毒;FLUB;FLUBV;乙型流感;乙型流感病毒;流感 B;流感 B 型;流感乙型;流感病毒乙型 FLUV;Influ;列性感冒病毒;流行性感冒病毒 II SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 分离出的;分离的;已分离的;检出的;经分离的;经过分离的;经过鉴定的;经鉴定的;鉴定的 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 受检物 呼吸道标本（样品、样本）;呼吸系统标本（样品、样本） 存在;存在与否;特征标识;身份;身份标识 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 样品 样本 流感病毒 A（流行性感冒病毒 A、甲型流感病毒、甲流病毒、甲流、FLUAV） & 流感病毒 B（流行性感冒病毒 B、乙型流感病毒、乙流病毒、乙流、FLUBV） & SARS 冠状病毒 2（SARS-CoV-2、新冠病毒、COVID-19 病毒）;2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute resp 经过扩增的 脱氧核糖核酸探针 试样